Saturday, August 22, 2009

Drugs and seizures

I was pondering about the mechanism behind drug-induced seizures.... except for most materials encountered address only the correlation between drugs and seizures. They do not talk about the "how."

Finally, I found in the following book "The Medical treatment of epilepsy" (1992) the passage: "The mechanism by which the antipsychotic agents affect the seizures threshold is unknown."

The only problem is that, the text is almost 20 years old and not quite sure whether there are breakthroughs in model building.... in addition to the dopamine model.

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