Thursday, May 21, 2009

Dopamine and depression

After last night's posting about Nicotine, Serotonin and Dopamine, something is still not quite settling in me... sort of like, the rationale was built half-way...


Even with bullshitting, the arguments gotta be cogent enough...

Then, I came across the following postmortem study of them courageous lab rats, depressive or not...

Essentially, there were two groups of rats used in this study: the depressive rats and the normal rats. It seemed like the authors measured the binding of chemicals to DA transporters and dopamine receptors at different brain region. Based on their results, they concluded that, in rats, "DA depletion in rats can induce a reduction in the DA transporter and an upregulation of D2/D3 receptors, our data are consistent with the hypothesis that major depression is associated with a deficiency of mesolimbic DA."



And, of course, association is like correlations.... it is not necessarily causation.


Could it have anything to do with the depression I am trying to come out from?


God knows... I guess...

No comments: